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Comparison of the effectiveness of a two different local anaesthetic drug 10% lignocaine spray and EMLA cream in reducing pain during IV cannulation.

A comparison of 10% lignocaine spray versus eutectic mixture of 2.5% lidocaine and 2.5% prilocaine (EMLA) to attenuate pain of peripheral venous cannulation in adults: A prospective randomised single-blind placebo-controlled trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/02/062548
Enrollment
90
Registered
2024-02-12
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 10% Lignocaine spray: 10% Lignocaine spray will be applied at the proposed site of IV cannulation 20 minutes prior to cannulation. Pain will be assessed by VAS score. VAS score will be

Sponsors

Nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American society of anesthesiology (ASA I to IV)

Exclusion criteria

Exclusion criteria: Refusal to participate Difficult iv cannulations Any burns, ulceration, erythema and infected skin · Any allergic to amide local anaesthetic History of deep vein thrombosis or any other vascular disorder · History of cardiac disease or migraine headachesPregnant or lactating females.

Design outcomes

Primary

MeasureTime frame
To Assess and compare degree of severity of pain during IV cannulation using the visual analogue scale (VAS) pain score Timepoint: Immediately after cannulation and 10 mins later—

Secondary

MeasureTime frame
To observe any change in hemodynamics – BP, HR, SPO2 after topical application of study drugs. To assess and compare the ease of cannulation To assess and compare the incidence of adverse effects if any in both the groupsTimepoint: Upto 30 mins post cannulation—

Countries

India

Contacts

Public ContactDr Gayatri Mishra

Mahatma Gandhi Medical College and Research Institute

drgayatrimishra@gmail.com9894354068

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026