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A clinical study to see the impact of phenylephrine drug infusion on body temperature during spinal anesthesia in parturients undergoing caesarean section

Effect of Phenylephrine on body temperature during elective and emergency caesarean delivery under spinal anaesthesia: a randomized clinical trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/02/062506
Enrollment
100
Registered
2024-02-12
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Phenylephrine group: Just before giving spinal anesthesia, intervention patients will be given phenylephrine infusion at 0.5mcg/kg/min and continued till the end of surgery Control Inte

Sponsors

All India Institute of Medical Sciences Patna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Pregnant women 18-45 years of age planned for cesarean section under spinal anesthesia will be included in the study. 1. Age between 18 and 65 years 2. ASA-PS Grade 2

Exclusion criteria

Exclusion criteria: Patient refusal to participate in the study Hypertensive disorders of pregnancy Cardiac diseases Antepartum haemorrhage Known allergy to drugs Thyroid disease Raynaud’s Disease Fever

Design outcomes

Primary

MeasureTime frame
To evaluate the change in core temperature with and without phenylephrine infusion using an infrared tympanometer in patients undergoing cesarean section under spinal anesthesiaTimepoint: Just before induction till end of surgery.

Secondary

MeasureTime frame
To evaluate the differences in surface temperature with and without phenylephrine To compare the incidence and severity of shivering To evaluate the incidence and frequency of bradycardia and hypotension To determine APGAR scores at one and five minutesTimepoint: Just before induction till end of surgery

Countries

India

Contacts

Public ContactDr Kunal Singh

All India Institute of Medical Sciences Patna

drsinghkunal@gmail.com9411514945

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026