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premedication with nebulization to decrease operative anxiety

Comparison of the effectiveness of preoperative dexmedetomidine nebulization versus lignocaine nebulization in attenuation of stress response during direct laryngoscopy and intubation in elective surgeries - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/02/062487
Enrollment
60
Registered
2024-02-09
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R098- Other specified symptoms and signsinvolving the circulatory and respiratory systems

Interventions

Intervention1: dexmedetomidine: 1 mcg/kg dexmedetomidine nebulization Control Intervention1: lignocaine: 1.5 mg/kg lignocaine 2% nebulization given preoperatively

Sponsors

Dr Kiran A V
Lead Sponsor
Dr Sumayya E
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing elective surgeries under general endotracheal anesthesia. Patients who are giving informed written consent American society of anaesthesiologist (ASA) grade ? and ? Mallampati ? and ? Patients with body mass index less than 30

Exclusion criteria

Exclusion criteria: History of URTI in previous 2 weeks History of smoking Laryngoscopy time more than30 seconds More than 2 attempts at laryngoscopy and intubation Patients requiring manipulation of airway or instrumentation like oral airway stylet bougie external laryngeal maneuver Pregnant patients Patients with poor cardio pulmonary reserve Patients who are on antidepressants or antipsychotics

Design outcomes

Primary

MeasureTime frame
To Compare the Effectiveness of Preoperative Dexmedetomidine Nebulization Versus Lignocaine Nebulization in Attenuation of Stress Response During Direct Laryngoscopy and Intubation Timepoint: baseline followed by post nebulization for 10 minutes—

Secondary

MeasureTime frame
To describe side effects of nebulized Dexmedetomidine and nebulized LignocaineTimepoint: 10 minutes—

Countries

India

Contacts

Public ContactDr sumayya e

Mandya Institute of Medical Sciences

virupaksha2614@yahoo.com8073147191

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026