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A study to predict the course of disease using alternative marker in patients with severe infection

Prognostic value of prothrombin time - international normalised ratio to albumin ratio in patients with sepsis - NIL

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/02/062479
Enrollment
140
Registered
2024-02-09
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A419- Sepsis, unspecified organism

Interventions

Sponsors

Dr Sanchit Mittal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients admitted with the diagnosis of Sepsis in Kasturba Hospital, Manipal under the Department of General medicine 2) quick sequential organ failure assessment score (qSOFA) of 2 or more in patients with presumed infection will be used to define sepsis

Exclusion criteria

Exclusion criteria: 1) Lack of PT-INR or albumin data within 24 hours of diagnosis of sepsis. 2) Pregnant patients 3) Patients with Malignancy 4) Patients on Anti coagulation therapy 5) Liver transplantation 6) Renal diseases like Nephrotic and Nephritic syndrome 7) Obstructive jaundice 8) Patients who have received Albumin or undergone plasmapheresis

Design outcomes

Primary

MeasureTime frame
To calculate the PT-INR to Albumin ratio in patients with sepsis and it’s prognostic efficiency in predicting patient outcome.Timepoint: At the time of discharge or death

Secondary

MeasureTime frame
? To compare the PT-INR to Albumin score with APACHE II score in predicting mortality in patients with sepsisTimepoint: At the time of discharge or death;? To correlate the PT-INR to Albumin ratio with requirement of Mechanical Ventilation, Hemodialysis and Inotropes.Timepoint: During the hospital stay of patient

Countries

India

Contacts

Public ContactDr Poonam Kamath

Kasturba Medical College, MAHE, Manipal

sanchitmittal29@yahoo.in8826729551

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026