Use of injectable amisulpride and ondansetron medicine for reduction of nausea and vomiting after gynecological laparoscopic surgery operation.

Comparison of intravenous amisulpride and ondansetron for prevention of postoperative nausea and vomiting after gynaecological laparoscopy: a randomized clinical trial - Nil

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/062477

Enrollment

Registered

2024-02-09

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Amisulpride: amisulpride 5 mg diluted with 5 ml normal saline at the time of induction of anesthesia slowly over 2 minutes. Assessment period 24 hours Control Intervention1: Ondansetron

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade I and II Scheduled for laparoscopic surgery under general anesthesia

Exclusion criteria

Exclusion criteria: Allergy to any drug involved in the study History of other antiemetic drug usage and motion sickness Morbid obesity Emergency surgery History of alcohol opioid and drug abuse Psychiatric and pregnant patients

Design outcomes

Primary

Measure	Time frame
Incidence and severity of nausea and vomitingTimepoint: assessment periods: 0–2 hr, 2–6 hr and 6–24 h after surgery.	—

Secondary

Measure	Time frame
Requirement of rescue antiemetic and patients satisfaction scoreTimepoint: Assessment periods: 0–2 hr, 2–6 hr and 6–24 h after surgery.	—

Countries

India

Contacts

Public ContactDr Vinit Kumar Srivastava

Apollo Hospitals Bilaspur

drvinit75@gmail.com9755557539

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026