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To study the effects of a Compound Unani Formulation in patients with Low sperm Count

Evaluating the therapeutic effects of Safuf-e-Talmakhana in the management of Qillat-e-Haiwain-e-Manviya (Oligospermia): A randomised, open-label study with standard control - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/02/062475
Enrollment
40
Registered
2024-02-09
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N461- Oligospermia

Interventions

Intervention1: safuf(powder): It is a classical unani formulation taken from Al-Qarabadeen.The formulation comprises of five herbal drugs namely Talmakhana (Asteracantha longifolia), Musli safed (Chl

Sponsors

Central Research Institute of Unani Medicine (CCRUM), New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Sperm count less than 20 million per ml. Married patients between 21 to 50 years of age Patients willing to sign written informed consent.

Exclusion criteria

Exclusion criteria: 1) Diagnosed patients of Azoospermia and Aspermia. 2) Patients having history of genetic defects like Klinefelter’s Syndrome. 3) Patients having Hernia, Varicocele, Hypogonadism, Testicular Atrophy, Undescended Testis excluded by clinical examination. 4) Patients having Thyroid dysfunction. 5) Patients with cardiac diseases and chronic renal failure. 6) Patients having uncontrolled diabetes mellitus and Hypertension. 7) Patients who fail to follow up.

Design outcomes

Primary

MeasureTime frame
1) Change from baseline to day 57th in the sperm count. 2) Change in serum testosterone level on 57th day. 3) Change in serum LH and FSH level on 57th Day.Timepoint: 56 Days

Secondary

MeasureTime frame
1) Effect on sexual desire scale. 2) Effect on Performance and Orgasm scale.Timepoint: 56 days

Countries

India

Contacts

Public ContactDr Mohammad Abbas Raza

Regional Research Institute of Unani Medicine (RRIUM), Srinagar

hussainzaffar6@gmail.com7006021996

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026