Health Condition 1: M059- Rheumatoid arthritis with rheumatoid factor, unspecified
Conditions
Interventions
Intervention1: Safuf-e-Chobchini: The unani formulation Safuf-e-Chobchini is a unani pharmacopeial formulation commonly prescribed for waja-al-mufasil(arthritis).It contains eight herbal drugs namely
Sponsors
Central Council for Research in Unani Medicine , New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients in the age group of 18 to 65 years. 2.Patients irrespective of gender. 3.Patients who fulfill the criteria of the New American College of Rheumatology European League Against Rheumatism 2010 for the diagnosis of rheumatoid arthritis. 4. Patients, who are ready to sign the informed consent, follow the protocol and willing to participate in the clinical study voluntarily.
Exclusion criteria
Exclusion criteria: 1.Women who are pregnant, planning pregnancy, or breast feeding. 2.Patients with systemic,extra-articular manifestations of rheumatoid arthritis. 3.Patients having gouty arthritis and psoriatic arthritis. 4.Patients with history of systemic disease like uncontrolled diabetes mellitus and hypertension,hepatic dysfunction and impaired renal function. 5.Patients currently receiving or have received intra-articular treatment, oral or parenteral corticosteroids, or NSAIDs within 2 weeks, DMARDs or anticipated IFN therapy within 4 weeks prior to study entry. 6.Obese subjects with BMI =35
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Pain intensity 2. Joint swelling 3. Morning stiffness 4. Fatigue 5. Restricted movement of joints 6. Joint tendernessTimepoint: Day 0,Day 14, Day 28,Day 42 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.DAS 28 2.HAQ disability index score 3.Erythrocyte sedimentation rate (ESR) 4. Quantitative C -reactive protein (CRP) 5. Quantitative Rheumatoid factor (RF) 6.Quantitative Anti-citrullinated protein antibody (ACPA) 7. Interleukin 6 (IL-6) Timepoint: Day 0,Day 43 | — |
Countries
India
Contacts
Public ContactAbhar Qureshi
Regional Research Institute of Unani Medicine (RRIUM) , Srinagar
Outcome results
None listed