None listed
Conditions
Interventions
Intervention1: Dehydrated Human derived membrane: During periapical surgery, the infected tissue is removed and the bone defect which is formed is filled with human chorionic membrane provided by the
Sponsors
Faculty of Dental SciencesKing Georges Medical University
Eligibility
Inclusion criteria
Inclusion criteria: 1.All patients within 18–40 years of age. 2.Single rooted, anterior teeth with Periapical radiolucency indicated for surgery. 3.Patients who are not on any medication affecting periapical healing. (Corticosteroids, chemotherapeutic agents, non ?steroidal anti ? inflammatory drugs (NSAIDs), antibiotics, anticoagulants and drugs which reduce osteoclastic activity).
Exclusion criteria
Exclusion criteria: 1.Patients who did not give their consent for participating in the study. 2.Patients with any systemic diseases like diabetes mellitus, hypertension, hepatitis, Human immunodeficiency virus, bone disorders, auto immune disorders. 3. Surgical retreatment cases. 4. Patients with malignant tumors or undergoing chemotherapy, radiotherapy. 5. Pregnant females. 6. Patients with periodontally compromised teeth.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate change in the size of the periapical defect after endodontic surgery surgery utilizing PRF and Dehydrated human derived membrane.Timepoint: measurement of surface area of the periapical defect using ultrasound at baseline,1month and 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of Neo-angiogenesis in the periapical defect after endodontic surgery using color dopplerTimepoint: Evaluation of neo angiogenesis using color doppler at baseline,1 month & 6 months | — |
Countries
India
Contacts
Public ContactMamidala Jyothi
Faculty of Dental Sciences,King Georges Medical University
Outcome results
None listed