Skip to content

Treatment of infected teeth by bioactive materials

Outcome of pulpotomy with bioactive cements in teeth with clinical symptoms of irreversible pulpitis - a randomised clinical trial - Nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/02/062443
Enrollment
66
Registered
2024-02-08
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Use of Bioactive MATERIALS for treatment: 1. Local anaesthetic will be administered. 2. The tooth will be isolated with rubber dam. 3. The cavity will be prepared using a high speed rou

Sponsors

Army Dental Centre Research and Referral
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Clinical inclusion criteria: 1. Mandibular 1st and 2nd permanent mature molars with deep caries, (Caries reaching the inner quarter of dentine, but with a zone of hard or firm dentine between the caries and the pulp, which is radiographically detectable when located on an interproximal or occlusal surface.) and symptomatic irreversible pulpitis. (European Society of Endodontology 2019). 2. Patients of age groups 18 to 45 with permanent mature molars. 3. No abnormal tooth mobility or pockets or periodontal involvement, clinical swelling and pus exudate/fistula. 4. Positive exaggerated and prolonged response to cold test and electric pulp test. 5. Tooth which can be restored to its form and function. 6. Patients with no significant medical problems. 7. Patients with no history of use of NSAIDS 24 hrs before the procedure Radiographic inclusion criteria: 1. The radiolucent caries penetrating into at least three-quarters of the inner dentin thickness. (Bjorndal 2019) 2. Extremely deep carious lesions (Bjorndal 2019) will be excluded. 3. Tooth with periapical index up to 03.

Exclusion criteria

Exclusion criteria: Clinical exclusion criteria: 1. Sinus tract with or without pus discharge. 2. Bleeding from pulp exposure site could not be controlled within 10 min. 3. No response on pulp testing. 4. Tenderness on percussion present. Radiographic exclusion criteria: 1. Periapical index score of more than 03. 2. The presence of internal or pathologic external root resorption, calcification or pulp canal obliteration, open apex/immature teeth.

Design outcomes

Primary

MeasureTime frame
1. Evaluation of the postoperative painTimepoint: Every 24 hrs till 72 hrs

Secondary

MeasureTime frame
Evaluation of the outcome of full pulpotomy in mature permanent molars with PROROOT MTA, BIODENTINE and ENDOCEM MTA as pulp capping materials with clinical and radiographic follow up of03, 06 and 12 months.Timepoint: 03 06 09 months

Countries

India

Contacts

Public ContactMAJ Aashish Mittal

ARMY DENTAL CENTRE RESEARCH AND REFERRAL

nilavbhagabati@gmail.com8412015953

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026