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Evaluation of bony changes in mouth joint disorders using saliva

Comparative Evaluation of Condylar Changes in Temporomandibular Joint Disorder Patients Assessed by Salivary Biomarkers MMP3, IL1?, and PAI1 - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/02/062408
Enrollment
38
Registered
2024-02-07
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M255- Pain in joint

Interventions

Intervention1: Nil: Nil Control Intervention1: Nil: Nil

Sponsors

Gibi Babu Philip
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients on clinical examination who met RDC TMD criteria I Female patients

Exclusion criteria

Exclusion criteria: Congenital craniofacial disorders Previous treatment for TMJ disorders Previous orthodontic treatments History of trauma to the TMJ area

Design outcomes

Primary

MeasureTime frame
Compare the level of MMP3, IL1ß, PAI1 in TMD patients before and after treatment. Compare the level of MMP3, IL1ß, ,PAI1 in healthy and TMD patients Timepoint: 5 months—

Secondary

MeasureTime frame
To determine the level of MMP3, IL1ß,PAI1 in healthy patients To determine the level of MMP3, IL1ß,PAI1 in TMD patientsTimepoint: 1 month—

Countries

India

Contacts

Public ContactAlex Mathews Muruppel

Rajas Dental College

alexmuruppel@gmail.com7034671873

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026