COMPARATIVE STUDY OF DEXMEDETOMIDINE AND FENTANYL WITH 0.5% BUPIVACAINE INTRATHECALLY FOR SUBARACHNOID BLOCK IN LOWER ABDOMINAL SURGERY

COMPARATIVE STUDY OF DEXMEDITOMIDINE WITH 0.5% HYPERBARIC BUPIVACAINE AND FENTANYL WITH 0.5% HYPERBARIC BUPIVACAINE INTRATHECALLY FOR SUBARACHNOID BLOCK IN LOWER ABDOMINAL SURGERY - Nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/062396

Enrollment

Registered

2024-02-07

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K409- Unilateral inguinal hernia, without obstruction or gangrene Health Condition 2: K409- Unilateral inguinal hernia, without obstruction or gangrene

Interventions

Intervention1: Spinal Anaesthesia for lower abdominal surgeries (From the date of acceptance of thesis protocol to 18 months or completion of study, whichever is earlier): 2.5ml Bupivacaine heavy with

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with ASA grade I and II 2. Patients in the age group of 18-50 years, of either sex. 3. Patients undergoing lower abdominal surgeries.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
To evaluate the onset and duration of sensory and motor block using dexmedetomidine (10mcgs) and fentanyl (25mcgs) as an adjuvant to 0.5% Bupivacaine in subarachoid block for lower abdominal surgeries.Timepoint: 18 months	—

Secondary

Measure	Time frame
To evaluate the onset & duration of sensory & motor block. To observe hemodynamic changes (SBP, DBP, MAP, HR, Sp02). To assess post operative analgesia using visual analogue score (VAS score) To assess adverse effect of dexmedetomidine or fentanyl given intrathecally with hyperbaric 0.5% BupivacaineTimepoint: 18 months	—

Countries

India

Contacts

Public ContactDr Ajay Kumar Sinha

Government Medical College and Dr STM Hospital, Haldwani, Uttarakhand

sinhaak1961@gmail.com9897672301

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026