Examining the Impact of Different IV Fluids during Cancer Surgery: A Comparison of Ringer Lactate and Plasmalyte intravenous fluids in major tumour removal with heated chemotherapy during surgery.

Comparison of Lactate levels with Ringer Lactate v/s Plasmalyte as Intraoperative intravenous fluid in Cytoreductive Surgery + Hyperthermic Intraperitoneal Chemotherapy (CRS + HIPEC). - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/062356

Enrollment

Registered

2024-02-07

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C00-D49- Neoplasms

Interventions

Intervention1: Ringer Lactate: Ringer Lactate will be used as intravenous fluid in patients undergoing CRS HIPEC surgery and lactate levels will be noted. Duration: From starting of the surgery to pos

Eligibility

Inclusion criteria

Inclusion criteria: All patients who are treated with CRS + HIPEC at our institute.

Exclusion criteria

Exclusion criteria: Patient not willing to participate in the study.

Design outcomes

Primary

Measure	Time frame
Primary objective is to compare lactate levels with intravenous infusion of Ringer’s lactate versus Plasmalyte in patients undergoing CRS HIPEC surgery. Timepoint: At Baseline, before HIPEC, after HIPEC and post operative day 1	—

Secondary

Measure	Time frame
To compare changes in pH & electrolyte equilibrium (sodium, potassium, calcium & chloride) in the two groups. Timepoint: At Baseline, before HIPEC, after HIPEC & post operative day 1	—

Countries

India

Contacts

Public ContactDr Deep Vinod

Aster CMI Hospital

drdeepv94@gmail.com7012561987

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026