To assess the effect of two drugs with adjuvant in spinal anesthesia on post operative pain duration in pregnant women undergoing elective caesarean section

A randomized comparative study to assess the effect of intrathecal magnesium sulphate as an adjuvant to hyperbaric bupivacaine versus isobaric levobupivacaine on post operative analgesia in parturients undergoing elective caesarean section at SMS Medical college Jaipur - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/062220

Enrollment

Registered

2024-02-01

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O298- Other complications of anesthesiaduring pregnancy

Interventions

Intervention1: Spinal anaesthesia in elective caesarean section: To assess the effect of intrathecal magnesium sulphate 75 mg as an adjuvant to hyperbaric bupivacaine 10 mg versus isobaric levobupivac

Eligibility

Inclusion criteria

Inclusion criteria: 1. Written Informed consent for this study 2. Adult age group 3. Patients undergoing elective caesarean section 4. Gestational age 37-42 weeks 5. ASA Grade-?

Exclusion criteria

Exclusion criteria: 1. High risk pregnancy like intrauterine growth restriction, eclampsia, preeclampsia, short stature, twin Gestation, maternal cardiovascular disorders, Endocrine disorders, pulmonary disorders, Chronic kidney and liver disorders 2. Parturient with contraindications for neuraxial block like lack of consent, elevated ICP, preexisting neurological disease, severe dehydration, hypovolemia, thrombocytopenia, coagulopathy, history of allergy to study drug 3. Patient should not be a part of other study 4. Non co-operative patient

Design outcomes

Primary

Measure	Time frame
1. Mean duration of Post op analgesia. Timepoint: 1. 0 hrs 2. 1 hrs 3. 3 hrs 4. 6 hrs 5. 12 hrs 6. 24 hrs	—

Secondary

Measure	Time frame
1. Mean time of onset of sensory block (minutes). 2. Mean time of onset of motor block (minutes). 3. Mean time taken for sensory regression of two segments (minutes). 4. Mean time taken for complete motor recovery (minutes). 5. Mean duration of sensory block (minutes). 6. Mean duration of motor block (minutes). 7. Mean haemodynamic parameters. (HR, SBP, DBP, MAP). 8. Mean APGAR score. Timepoint: 1. 2 min. 2. 4 min. 3. 6 min. 4. 8 min. 5. 10 min. 6. 15 min. 7. 20 min. 8. 25 min. 9. 30 min. 10. 40 min. 11. 50 min. 12. 60 min.	—

Measure

Time frame

1. Mean time of onset of sensory block (minutes). 2. Mean time of onset of motor block (minutes). 3. Mean time taken for sensory regression of two segments (minutes). 4. Mean time taken for complete motor recovery (minutes). 5. Mean duration of sensory block (minutes). 6. Mean duration of motor block (minutes). 7. Mean haemodynamic parameters. (HR, SBP, DBP, MAP). 8. Mean APGAR score. Timepoint: 1. 2 min. 2. 4 min. 3. 6 min. 4. 8 min. 5. 10 min. 6. 15 min. 7. 20 min. 8. 25 min. 9. 30 min. 10. 40 min. 11. 50 min. 12. 60 min.

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Countries

India

Contacts

Public ContactDr Shravan kumar jat

Department of anaesthesia sawai man singh medical college and attached hospital jaipur

drsavita020@gmail.com8290969216

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026