A study comparing the oral care with chlorhexidine is better when compared with multicomponent bundle without chlorhexidine in ventilation patients for prevention of pneumonia.

A Comparative Study To Find Out The Efficacy Of Oral Care With Chlorhedinine Versus Multicomponent Bundle Without Chlorhexidine In Mechanical Ventilated Patients In Intensive Care Unit - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/062201

Enrollment

1286

Registered

2024-02-01

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J22- Unspecified acute lower respiratory infection

Interventions

Intervention1: CHLORHEXIDINE GROUP: the intervention group will be given oral care with multicomponent care bundle includes 0.20% chlorhexidine solution 5-10ml orally, every 12 hrly and tooth brushing

Eligibility

Inclusion criteria

Inclusion criteria: 1. Admitted to the ICU and requiring mechanical ventilation. 2. Anticipated to require mechanical ventilation for more than 48 hours. 3. Patient or legal representative has provided informed consent.

Exclusion criteria

Exclusion criteria: ? Patients with known hypersensitivity or allergy to Chlorhexidine. ? Patients already in another oral care study. ? Patients with severe oral trauma or recent oral surgery. ? Patients with a life expectancy of less than 48hrs Patients for whom oral care maybe contraindicated due to specific medical conditions. (e.g. certain types of oral cancer, certain neurological conditions affecting swallowing).

Design outcomes

Primary

Measure	Time frame
Incidence of IVACs between control and intervention groups during ventilator days.Timepoint: 6 weeks of ICU stay	—

Secondary

Measure	Time frame
To evaluate 1.oral health status dysfunction measured using BOAS Beck oral assessment score 2.CPOT Critical care pain observation, 3. ventilator days, 4. ICU stay, 5. 28 day mortality, 6. VAP incidence Timepoint: till 5 weeks	—

Countries

India

Contacts

Public ContactRohit Kumar Patnaik

IMS AND SUM HOSPITAL, BHUBANESWAR

Rohitpatnaik09@gmail.com9833116430

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026