Optimal dose of dexmedetomidine as an adjuvant to ropivacaine 0.75% with dextrose 80mg used in spinal anesthesia in patients undergoing lower abdominal and lower limb surgeries

Optimal dose of intrathecal dexmedetomidine as an adjuvant to hyperbaric ropivacaine in subarachnoid block in patients undergoing lower abdominal and lower limb surgeries - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/02/062187

Enrollment

100

Registered

2024-02-01

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Group D1 (dexmedetomidine 5mcg): A drug volume of 3.2ml containing 3ml of hyperbaric ropivacaine hydrochloride (7.5mg per ml) along with dexmedetomidine (available as 100mcg per ml) 5mc

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients scheduled for elective lower abdominal and lower limb surgeries under subarachnoid block in VMMCH, Karaikal. 2) Patients of American Society of Anaesthesiologists (ASA) physical status I and II

Exclusion criteria

Exclusion criteria: 1) Patients allergic to any of the drugs used 2) Patients having any absolute contraindications for spinal anesthesia such as patient not willing raised intracranial pressure, severe hypovolemia, bleeding diathesis, local infection and cardiac respiratory, and CNS diseases 3) Patients having hypertension 4) Patients with obesity more than 30kg per meter square 5) Patient with height less than 150cms

Design outcomes

Primary

Measure	Time frame
To compare Total duration of analgesia and Post-operative analgesia of intrathecal dexmedetomidine as an adjuvant to hyperbaric ropivacaine in subarachnoid block in patients undergoing lower abdominal and lower limb surgeriesTimepoint: Time of drug given to 10th hour of postoperative period	—

Secondary

Measure	Time frame
To compare 1)Onset of sensory blockade Onset and duration of motor blockade 2)Hemodynamic changes such as hypotension and bradycardia 3)Side effects such as pruritus, nausea and vomiting, shivering, urinary retention, and respiratory depression.Timepoint: time of drug given to 10th hour of postoperative period	—

Countries

India

Contacts

Public ContactDr Abhisheak Raveendran

Vinayaka Missions Medical College, Karaikal

anscheran.k73@gmail.com9443144652

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026