Adaptive support mode a new advanced mode versus routine conventional ventilation in ventilation of children requiring mechanical ventilation Trial

Effect of Adaptive Support Ventilation when compared with Conventional Ventilation in mechanically ventilated children – A Randomized Control Trial - ADVENT Trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/062156

Enrollment

100

Registered

2024-01-31

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J22- Unspecified acute lower respiratory infection

Interventions

Intervention1: Adaptive support mode of ventilation: Patient after randomization will be started on adaptive support mode of ventilation a new mode of ventilation Control Intervention1: Routine mode o

Eligibility

Inclusion criteria

Inclusion criteria: Children from 1 month to =15 years of age with acute need for invasive mechanical ventilation inclusive of acute respiratory illness, congenital heart disease, post cardiac surgery, acute neurological diseases and multi-organ dysfunction by oral endotracheal tube

Exclusion criteria

Exclusion criteria: Expected death within 24 hours of intubation Refusal to consent

Design outcomes

Primary

Measure	Time frame
Duration of ventilationTimepoint: Till 28 days from the date of enrollment	—

Secondary

Measure	Time frame
Extubation failure Length of PICU stay Mortality Oxygenation saturation index Timepoint: Admission to PICU discharge	—

Countries

India

Contacts

Public ContactAbinaya Kannan

All India Institute of Medical Sciences

drmrsahoo@gmail.com7898368010

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026