A study to understand the patients point of view (anxiety level and pain score) undergoing bone marrow first time, the total cost spent towards bone marrow procedure and benefit of the Tramadol in controlling pain if given along with the local anesthesia during bone marrow procedure.

Assessment of patient perceptions, resource utilisation and utility of tramadol as pre-procedural analgesia in bone marrow aspiration and biopsy. - BMAB study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/062117

Enrollment

176

Registered

2024-01-31

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C910- Acute lymphoblastic leukemia [ALL] Health Condition 2: C920- Acute myeloblastic leukemia Health Condition 3: C919- Lymphoid leukemia, unspecified Health Condition 4: C929- Myeloid leukemia, unspecified Health Condition 5: C96Z- Other specified malignant neoplasms of lymphoid, hematopoietic and related tissue

Interventions

Intervention1: 50 mg oral Tramadol in addition to the standard local infiltration of lignocaine (as LA): Dose 50 mg Route Oral Frequency Once a time Time point Prior to the Bone Marrow Procedure Contr

Eligibility

Inclusion criteria

Inclusion criteria: Age Criteria: 15 Years or older Patients who have been planned to undergo BMAB at our center (at diagnosis or response assessment)

Exclusion criteria

Exclusion criteria: Patients refusing to give informed consent for BMAB procedure or for the study. Patients who have received premedication with any sedative, analgesic or any other CNS depressant, 30 min before the BMAB or ongoing use of these drugs. Patients who are on Carbamazepine, a hepatic enzyme inducer. History of opioid dependency or addiction. Known cases of allergy or hypersensitivity with use of opioids.

Design outcomes

Primary

Measure	Time frame
Mean pain scoresTimepoint: Immediately after the procedure 24 hours after the procedure	—

Secondary

Measure	Time frame
Anxiety scores Direct costs of the procedureTimepoint: Immediately after the procedure 24 hours after the procedure	—

Countries

India

Contacts

Public ContactDr Alok Parekh

Tata Memorial Hospital

manju.sengar@gmail.com22241770007211

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026