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Measuring A Disintegrin and Metalloproteinase 17 Marker levels in diabetic and obese patients with periodontitis

A COMPARATIVE EVALUATION OF A DISINTEGRIN AND METALLOPROTEINASE (ADAM )17 MARKER RESPONSE TO PERIODONTAL THERAPY IN DIABETES AND OBESE PATIENTS WITH AND WITHOUT PERIODONTITIS. - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/01/062104
Enrollment
160
Registered
2024-01-31
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Group 1(20) – a. diabetics with periodontitis(10)Serum will be collected from the patients at baseline and 3 months after periodontal therapy b. diabetics without periodontitis(10): 3

Sponsors

Panineeya Mahavidyalaya Institute of Dental Sciences and Research centrer
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Known diabetic patients(Test group) patients with BMI values greater than 30(test group) Individuals with moderate periodontitis( according to 2017 classification) Patients who have not received periodontal therapy within preceeding 3months. Patients should have atleast 15 teeth.

Exclusion criteria

Exclusion criteria: Presence of any other systemic diseases,genetic diseases,and diseases which effect periodontitium Smokers,tobacco chewers and alcholics. Patients with present and past history of antibiotics and anti inflammatory drugs in last 3 months. Patients taking high dose of steroid therapy,radiation therapy or immunosuppressive therapy and any other medication for systemic diseases.Pregnant and lactating women. patients undergoing treatment for obesity. Mentally challenged and un cooperative patients. Patients not complaint to oral hygiene instuctions and recall maintenance.

Design outcomes

Primary

MeasureTime frame
Is there any difference in ADAM 17 levels in diabetic and obese patients Is there any variation in the ADAM 17 levels before and after periodontal therapyTimepoint: BASE LINE AND 3 MONTHS

Secondary

MeasureTime frame
Is there any variation in the clinical parameters after periodontal therapyTimepoint: BASE LINE AND 3 MONTHS

Countries

India

Contacts

Public ContactMUTHYALA SOUMYA SAGAR

Panineeya Mahavidyalaya Institute of Dental Sciences and Researchcentre

surya.prasanna@yahoo.com9440387830

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026