Nalbuphine vs fentanyl as additive to main drug bupivacaine in spinal anaesthesia.

Comparison of intrathecal nalbuphine and fentanyl as adjuvants to bupivacaine in spinal anaesthesia in patients undergoing lower limb surgeries. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/062089

Enrollment

100

Registered

2024-01-31

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Intrathecal nalbuphine as adjuvants to heavy bupivacaine in spinal anesthesia in patients undergoing lower limb surgeries.: The solution will be prepared in a five ml syringe which will

Eligibility

Inclusion criteria

Inclusion criteria: 1.American society of anaesthesiologist(ASA) status I and II 2.Age 25-65 years 3.both genders.

Exclusion criteria

Exclusion criteria: 1.Patients with contraindication to spinal anaesthesia 2.Pre-existing neurological deficits 3.Patients with history of allergy to study drugs 4.Pregnant patients.

Design outcomes

Primary

Measure	Time frame
To evaluate & compare the following factors in two groups-intrathecal nalbuphine & intrathecal fentanyl as an adjuvant to hyperbaric bupivacaine in lower limb surgeries with respect to: 1. Sensory & motor blockade -onset & durationTimepoint: Time at which intrathecal drug is administered is T0, followed by T1 at 1min,T2 at 2 min,T3 at 3 min interval......till intraoperative period followed by time required for regaining of sensory and motor sensation in postoperative period.	—

Measure

Time frame

To evaluate & compare the following factors in two groups-intrathecal nalbuphine & intrathecal fentanyl as an adjuvant to hyperbaric bupivacaine in lower limb surgeries with respect to: 1. Sensory & motor blockade -onset & durationTimepoint: Time at which intrathecal drug is administered is T0, followed by T1 at 1min,T2 at 2 min,T3 at 3 min interval......till intraoperative period followed by time required for regaining of sensory and motor sensation in postoperative period.

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Secondary

Measure	Time frame
Duration of analgesiaTimepoint: perioperative to postoperative period	—

Countries

India

Contacts

Public ContactDr Suneeta Dutta

Silchar medical college and hospital

drsuneetadutta@gmail.com9435074110

Outcome results