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Comparison of efficacy of Dexamethasone vs Dexmedetomidine as adjuvants with Ropivacaine in Scalp Nerve Block for patients undergoing Awake Craniotomy: A Randomised Controlled Trial

Comparison of efficacy of Dexamethasone vs Dexmedetomidine as an adjuvants with Ropivacaine in Scalp Nerve Block for patients undergoing Awake Craniotomy: A Randomised Controlled Trial - NIL

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/01/062046
Enrollment
50
Registered
2024-01-30
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C719- Malignant neoplasm of brain, unspecified

Interventions

Intervention1: Scalp Nerve Block in awake craniotomy surgeries.: Scalp nerve block is a type of regional anesthesia that involves injecting a local anesthetic solution into specific nerves in the scal

Sponsors

PGIMER Chandigarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: With body mass index (BMI) of 18.5– 29.9 kg/m2, belonging to ASA physical status of 1 or 2, scheduled for elective awake craniotomy

Exclusion criteria

Exclusion criteria: Refusal of the patient Pregnancy, bleeding disorder Patients receiving sedatives Psychological disturbances Alcohol or substance abuse Presence of cardiac or respiratory disease ? Local infection at site of injection ? Patients with known allergy to any of the study drugs ? Coagulopathy ? Hepatic or Renal impairment

Design outcomes

Primary

MeasureTime frame
To compare the time interval of the the first dose of rescue analgesia during perioperative period. (Defined as the duration between onset of sensory blockade to the first use of rescue analgesic drug as demanded by the patient (NRS = 4). Timepoint: Till 24 hrs

Secondary

MeasureTime frame
1. To compare the time needed for onset of sensory block (will be checked by loss of pin prick sensation at every 2 min). 2.To see intraoperative hemodynamic response after adding adjuvants to ropivacaine in scalp block, measured using HR & MAP. 3.Incidence of intra operative & 24hr post operative pain measured using NRS score. 4.Total consumption of rescue analgesic drug in 24 hrs postoperatively. 5.Intraoperative & postoperative complications such as nausea, vomiting, oversedation, respiratory depression, bradycardia, hypotension, failure of block, conversion to GA will be recorded. Timepoint: Till 24 hrs

Countries

India

Contacts

Public ContactLeena Sharma

Post Graduate Institute of Medical Education and Research, Chandigarh

dr.rajeevchauhan@gmail.com7087422950

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026