Health Condition 1: G988- Other disorders of nervous system
Conditions
Interventions
Intervention1: NA: NA
Control Intervention1: NA: NA
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients undergoing intracranial neurosurgery under general anaesthesia and maintained on either isoflurane or sevoflurane 2. American Society of Anaesthesiologist (ASA) grade I or II
Exclusion criteria
Exclusion criteria: 1. Diagnosed patients of pituitary adenoma on CT 2. Previous History of neurosurgery 3. History suggestive of allergies to isoflurane or sevoflurane 4. Patients with comorbidities like Hypertension and Diabetes Mellitus. 5. Pregnant women 6. Patients with history of malignant hyperthermia, preexisting renal insufficiency, Hepatic disease, Endocrine disease, Neurological abnormality and electrolyte abnormalities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recovery end-points were measured as the time from closure of anesthesia to various time intervals of the anaesthetic vaporizer. • Difference in patients achieving recovery profileTimepoint: NA | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Difference in the Blood pressure and Heart Rate of isoflurane and sevoflurane from baseline to various time intervals 2. To assess the safety of isoflurane and sevoflurane in terms of adverse events (alteration of hemodynamics and adverse drug reaction)Timepoint: 1 Blood Pressure and Heart Rates were measured (1hour,2hour,3hour,4hour,5hour) intraoperatively 2 Adverse events were seen perioperatively and postoperatively upto 2 hours | — |
Countries
India
Contacts
Public ContactDr Nikhil Mujbaile
GMCH, Nagpur
Outcome results
None listed