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can supporting babys breaths without tube after removing the endotracheal tube reduce the need of re insertion of the endotracheal tube

role of non-invasive ventilation in reducing extubation failure in term neonates - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/01/062020
Enrollment
105
Registered
2024-01-30
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P039- Newborn affected by complication of labor and delivery, unspecified

Interventions

Intervention1: continuous positive airway pressure: Term neonates on mechanical ventilation will receive nasal continuous positive pressure ventilation (CPAP) through a bubble CPAP machine immediately

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: all term babies (gestational age = 37 weeks) on mechanical ventilation when ready for extubation will be included in the study.

Exclusion criteria

Exclusion criteria: i) major congenital malformation ii) genetic syndromes iii) babies who underwent gastrointestinal surgery iv) airway malformations

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of nasal CPAP (CPAP), heated humidified high flow nasal cannula (HFNC) and low flow oxygen (LFO) in reducing extubation failure within 72 hours of extubation in term babies.Timepoint: To compare the efficacy of nasal CPAP (CPAP), heated humidified high flow nasal cannula (HFNC) and low flow oxygen (LFO) in reducing extubation failure within 72 hours of extubation in term babies.

Secondary

MeasureTime frame
i) to study the profile of term neonates on mechanical ventilation ii) To study the other secondary outcomes i) need for reintubation, ii) duration of oxygen need, iii) duration of hospital stay & iv) mortality in the three groups Timepoint: 24,48,72 hours of extubation

Countries

India

Contacts

Public ContactRuchi Rai

Postgraduate Institute of Child Health, Sector 30, Noida

ruchiraialld@gmail.com08874628287

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026