Use of LASER light in Root Canal Treatment (RCT)

Outcome of nonsurgical root canal treatment after photodynamic therapy in patients with symptomatic apical periodontitis â?? A Randomized Clinical Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/062010

Enrollment

Registered

2024-01-30

Start date

Unknown

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K044- Acute apical periodontitis of pulpal origin

Interventions

Intervention1: Photodynamic therapy(During Root Canal Treatment): In the Intervention group 1. Photosensitizer dye (phenothiazine chloride) will be applied in the root canals and left inside for 60 se

Eligibility

Inclusion criteria

Inclusion criteria: Mandibular first and second molars with a diagnosis of pulpal necrosis (confirmed by negative cold test and EPT) and symptomatic apical periodontitis having periapical index score >= 3.

Exclusion criteria

Exclusion criteria: 1. Antibiotic usage within the last month or anti-inflammatory therapy 2. Patients with uncontrolled Systemic disorders, pregnancy and lactation. 3. Canal curvature more than 20 degrees (Schneiderâ??s method). 4. Anatomical complexities such as C shaped canals, taurodont, entomolaris 5. Traumatic occlusion. 6. Calcified canals and root resorption. 7. Periodontally compromised teeth or sinus tracts. 8. Severe crown destruction preventing rubber dam application.

Design outcomes

Primary

Measure	Time frame
periapical healing using periapical index (PAI) scoreTimepoint: 03 MONTHS 06 MONTHS 09 MONTHS	—

Secondary

Measure	Time frame
incidence & severity of painTimepoint: 24HR,48HR, 72HR	—

Countries

India

Contacts

Public ContactMaj Dipendra Karndhar

Army Dental Centre Research and Referral

nilavbhagabati@gmail.com08412015953

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026