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Comparative study of efficacy of 3 drugs in spinal anesthesia isobaric ropivacaine 0.5%, heavy ropivacaine and bupivacaine heavy

A comparative study of efficacy of intrathecal isobaric ropivacaine 0.5% , ropivacaine heavy and bupivacaine heavy for lower abdomen and lower limb surgeries - Nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/01/062008
Enrollment
120
Registered
2024-01-30
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S720- Fracture of head and neck of femur Health Condition 2: S823- Fracture of lower end of tibia Health Condition 3: S820- Fracture of patella Health Condition 4: S824- Fracture of shaft of fibula Health Condition 5: S822- Fracture of shaft of tibia Health Condition 6: S822- Fracture of shaft of tibia Health Condition 7: S828- Other fractures of lower leg Health Condition 8: E136- Other specified diabetes mellituswith other specified complications Health Condition 9: K631- P

Interventions

Intervention1: NIL: NIL Control Intervention1: Isobaric Ropivacaine: Intrathecal Isobaric Ropivacaine 3ml (0.5%) (40 patient each of total duration 18 months) Control Intervention2: Bupivacaine Heavy:

Sponsors

Archana Singh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Patient giving consent to participate in study 2 Age between 18-60 years 3 Weight between 40-90 kg 4 SA grade I and II

Exclusion criteria

Exclusion criteria: •Patients not giving consent to participate in the study. •ASA grade III and IV •Renal dysfunction •Cardiac disease •Patient with elevated AST,ALT values •History of bleeding disorders

Design outcomes

Primary

MeasureTime frame
Intrathecal Hyperbaric Ropivacaine 0.5% provides clinically effective anesthesia in Lower limb and Lower abdomen surgeries with short duration of motor block , similar duration of sensory blockade ,height of block ,hemodynamic and adequate Post operative analgesiaTimepoint: 18 Months

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr Ashish Mathur

Gajra Raja Medical College, Gwalior M.P.

ashishgrmc2012@gmail.com8989874707

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026