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Comparison of 2 antibiotics in treatment of ventilator induced lung infectiopn

comparison of meropenem based triple therapy versus minocycline based triple therapy for treatment of carbapenem resistant acinetobacter baumanii(CRAB) ventilator associated pneumonia - A prospective observational study - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/01/062000
Enrollment
200
Registered
2024-01-29
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J168- Pneumonia due to other specified infectious organisms

Interventions

Intervention1: NIL: NIL Intervention2: NIL: NIL

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged >18 years Patients having CRAB in tracheal aspirate of Ventilator associated pneumonia (VAP) patients according to culture report

Exclusion criteria

Exclusion criteria: The patient/relatives who refuse to give informed consent Age less than 18 years Pregnant females Moribund and Brain dead patients Patients with known allergy to given drug regime

Design outcomes

Primary

MeasureTime frame
Patient treated with minocycline based triple thrapy will have better clinical cure rate and faster microbiological clearance as compared to meropenem based triple therapyTimepoint: 72 HOURS—

Secondary

MeasureTime frame
Mortality rate at 7 & 28 day , length of hospital stay & icu stay will be decreased.Timepoint: 72 HOURS—

Countries

India

Contacts

Public ContactPrajapati Jinalben Kishorbhai

AIIMS JODHPUR

tanvimeshram162@gmail.com9968480167

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026