Health Condition 1: I083- Combined rheumatic disorders of mitral, aortic and tricuspid valves
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All patients with American Society of Anaesthesiologists Physical Status 3 or 4 of age 20 to 60 years planned for elective open heart surgery under cardiopulmonary bypass
Exclusion criteria
Exclusion criteria: Patients with history of severe hepatic renal dysfunction and Chronic obstructive pulmonary disease with FEV1 less than 50 percent Patients with cyanotic heart disease Patients with left ventricular ejection fraction less than 40 percent Patients undergoing combined surgical procedures CABG combined with valve surgery or aortic procedures and carotid surgery Redo-procedures within one year of previous surgery Patients with serum lactate more than 3 mmol per litre preoperatively Patients with BMI of more than 32 kg per meter square Pregnant patients Patients with sepsis and shock states Patients with nail pathologies Patients in whom modified Allens test could not be performed or is negative
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare and correlate the peripheral perfusion index with serum lactate levelsTimepoint: T1 preCPB T2 cooling T3 hypothermia T4 rewarming T5 post- CPB T6 6 hours postoperatively T7 12 hours postoperatively T8 24 hours postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| To correlate changes in peripheral perfusion index & serum lactate values with changes in haemodynamic indicesTimepoint: T1 pre CPB T2 cooling T3 hypothermia T4 rewarming T5 post- CPB T6 6 hours postoperatively T7 12 hours postoperatively T8 24 hours postoperatively | — |
Countries
India
Contacts
Pt BD Sharma PGIMS Rohtak