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Scientific testing of a method called Acute Normovolemic Haemodilution to save blood during surgery for major urological cancer

Acute Normovolemic Haemodilution in Urological malignancies: A randomized control study at a tertiary cancer center in Northern India - NIL

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/01/061994
Enrollment
178
Registered
2024-01-29
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Acute Normovolemic Haemodilution: The patients randomized to the intervention arm will receive autologous blood intraoperatively whenever there is an indication for transfusion. The blo

Sponsors

Mahamana Pandit Madan mohan Malaviya Cancer Centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Consenting patients of Surgical Urology posted for Radical cystecomy, resection of large masses with or without Inferior vena cava involvement, open radical prostatectomy, retroperitoneal lymph node dissection, partial nephrectomy, nephroureterectomy. The presurgical Hb of the patient must be within 12 to 16.5gper dL

Exclusion criteria

Exclusion criteria: Non consenting patients, Active or history of coronary artery disease, cerebrovascular accident, chronic obstructive pulmonary disorder, renal dysfunction, liver dysfunction, abnormal coagulation parameters, active infection, Hb more than 16.5 and less than 12gperdL, history of allogeneic blood transfusion within 3 months of surgery, emergency surgeries and reexploration surgeries

Design outcomes

Primary

MeasureTime frame
Number of allogeneic blood transfusions performed intraoperativelyTimepoint: From the beginning of the surgery till the end of the surgery

Secondary

MeasureTime frame
Morbidity and mortality in the form of Post operative complications assessed by Clavien Dindo classificationTimepoint: Upto 30 days following the surgery;Expenses incurred during the hospital stayTimepoint: Upto 30 days after the surgery;Length of hospital stayTimepoint: At the end of the hospital stay

Countries

India

Contacts

Public ContactDr Revathy Nair K

Mahamana Pandit Madan mohan Malaviya Cancer Centre, Varanasi

revathy@mpmmcc.tmc.gov.in8113847901

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026