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Salivary Interleukins-6 and 8: Role in diagnosis of oral cancer

Detection of interleukins-6 and 8 in saliva as possible biomarkers for oral pre-malignant lesions and oral cancer - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/01/061960
Enrollment
180
Registered
2024-01-29
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx

Interventions

Intervention1: Nil: Nil Control Intervention1: Nil: Nil

Sponsors

AIIMS, Rajkot
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: case subjects (patients) with a comprehensive and thorough clinical examination and confirmation by a biopsy Controls with no history of systemic illness

Exclusion criteria

Exclusion criteria: not willing to give written inform consent cases with gingivitis

Design outcomes

Primary

MeasureTime frame
The study will help in assessing the levels and diagnostic efficacy of salivary IL-6 and IL-8 levels in a particular geographic region with a high prevalence of PMLs and OSCC. The results will help in distinguishing PML from OSCC with a non-invasive, easily accessible tool that can be introduced in community screening programs as well.Timepoint: The study will assess salivary IL-6 and IL-8 levels at the baseline, before the start of treatment in oral cancer and cases with precancerous lesions

Secondary

MeasureTime frame
The results will help in distinguishing PML from OSCC with a non-invasive, easily accessible tool that can be introduced in community screening programs as well.Timepoint: 2 years

Countries

India

Contacts

Public ContactRagini Singh

AIIMS, Rajkot

singh.ragini28@yahoo.com9624000839

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026