Health Condition 1: D259- Leiomyoma of uterus, unspecified Health Condition 2: O- Medical and Surgical
Conditions
Interventions
Intervention1: Carbetocin infusion: To determine the intra-operative blood loss during elective abdominal myomectomy under sub-arachnoid block in patients to whom pre-operative Carbetocin infusion is
Sponsors
Institute of Post Graduate Medical Education and Research and SSKM Hospital Kolkata
Eligibility
Inclusion criteria
Inclusion criteria: 1. Body weight between 50 - 90 kgs 2. Symptomatic leiomyomas and scheduled to undergo abdominal myomectomy 3. With number of myoma = 5 4. Myoma FIGO staging 3 to 6
Exclusion criteria
Exclusion criteria: 1. Unwilling patient 2. Patients undergone vaginal or laparoscopic myomectomy 3. Patients received preoperative embolisation or GnRh analogue 4. Previous myomectomy 5. Pregnant and postmenopausal women 6. Myoma FIGO staging 1,2,7 & 8 7. Cervical and broad ligament myoma 8. Allergy or contraindications to Carbetocin such as coronary artery disease, asthma, epilepsy, migraine, kidney and hepatic diseases 9. Preoperative haemoglobin concentration less than 10 gm per dL
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Estimated intra-operative blood loss (mL)Timepoint: Intra-operative period | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Need for intraoperative and postoperative blood transfusion 2. Preoperative and postoperative haemoglobin values (measured after 6 and 24 hours of surgery) 3. Operative time 4. Duration of postoperative hospital stay 5. Drug-related adverse effects 6. Operative complications.Timepoint: Intra-operative period and Post-operative period | — |
Countries
India
Contacts
Public ContactDr Soma Chakraborty
Institute of Post Graduate Medical Education and Research (IPGME&R) and SSKM Hospital, Kolkata
Outcome results
None listed