Effectiveness of anaesthetic liquid vapour sevoflurane and desflurane from awakening under complete sleep anaesthesia in patients undergoing key hole gall blader operation patients in Regional Institute of Medical Sciences Hospital using randomly selection of patients.

Comparative study of recovery characteristics between sevoflurane and desflurane in laparoscopic cholecystectomy patients under general anaesthesia in Regional Institute of Medical Sciences Hospital- a randomized clinical trial. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061925

Enrollment

Registered

2024-01-29

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis Health Condition 2: K800- Calculus of gallbladder with acutecholecystitis

Interventions

Intervention1: Use of Desflurane during the maintenace period: Study participants will be randomized to receive desflurane in concentration decided by haemodynamics and bispectral index scoring for a

and Group B patients will receive Desflurane as maintenance agent with concentration decided by Bispectral Index Score (BIS) between 60- 40 and hemodynamics parameters with changes in heart rate and

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients of both sex with American Society of Anesthesiologist (ASA) physical grade I or II 2.Patients of age group 18 to 55 years of Manipuri ethnicity undergoing laparoscopic cholecystectomy under general anaesthesia.

Exclusion criteria

Exclusion criteria: 1.History of use of hypnotics or antipsychotics in the last 30 days 2.History of cerebrovascular diseases, chronic kidney diseases, significant cardiovascular diseases, chronic obstructive pulmonary diseases, etc. 3.Pregnant patient, patient refusal and history of allergy to any medication 4.Surgeries lasting more than one hour. 5.Body mass index more than 30

Design outcomes

Primary

Measure	Time frame
The primary outcome of this study will be the time interval from the stoppage of inhalational anaesthetics to the time to spontaneous eye opening, time to obey commands, time to extubation and time to reach modified Aldrete score of 9.Timepoint: The assesment will be done from the stoppage of inhalational anaesthetic to spontaneous recovery, i.e at 5 and 10 minutes after the stoppage.	—

Secondary

Measure	Time frame
The secondary outcomes will includehemodynamics parameters such as blood pressure and heart rate at 5 minutes, 10th minutes, thereafter for every 10 minutes and also at immediate postoperative period, side effects such as coughing, emergence agitation, nausea and vomiting, laryngospasm, excessive secretion, desaturation, etcTimepoint: The recording will be done at 5th, 10th, every 10 minutes intraoperatively and immediate postoperative	—

Measure

Time frame

The secondary outcomes will includehemodynamics parameters such as blood pressure and heart rate at 5 minutes, 10th minutes, thereafter for every 10 minutes and also at immediate postoperative period, side effects such as coughing, emergence agitation, nausea and vomiting, laryngospasm, excessive secretion, desaturation, etcTimepoint: The recording will be done at 5th, 10th, every 10 minutes intraoperatively and immediate postoperative

—

Countries

India

Contacts

Public ContactDr Takhelmayum Hemjit Singh

Regional Institute of Medical Sciences, Imphal West, Manipur

takhelhem@yahoo.com09436021445

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026