the placental transfusion in cut-umbilical cord milking vs Early cord clamping

Cut umbilical cord milking(C-UCM)as a mode of placental transfusion in twin pregnancies of 30-37 weeks gestation-a randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061865

Enrollment

166

Registered

2024-01-25

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I999- Unspecified disorder of circulatory system

Interventions

Intervention1: cut cord milking: cut cord milking as mode of placental transfusion in twin pregnancies of 30-37 weeks gestation Intervention2: cut cord miking: In both arms, the obstetrician shall cla

Eligibility

Inclusion criteria

Inclusion criteria: during the delivery time

Exclusion criteria

Exclusion criteria: i. Neonates born at gestation less than 30weeks or more than or equal to 37 weeks ii. Outborn neonates iii. Major lethal congenital anomalies or known/suspected chromosomal anomalies iv. Fetal hydrops v. Rh isoimmunization vi. Cord prolapse, cord abnormalities such as true knots vii. Twin-to-twin transfusion syndrome viii. Discordant twins (a weight difference of >20%) ix. Short umbilical cord length x. Noparentalconsent xi. Residence beyond 20 kms radius from our unit.

Design outcomes

Primary

Measure	Time frame
To determine venous hematocrit at 48 (+/- 4 ) hours of postnatal age Timepoint: To determine venous hematocrit at 48 (+/- 4 ) hours of postnatal age	—

Secondary

Measure	Time frame
a. Hct and serum ferritin at 6weeks of postnatal age b. Hb,hct and bilirubin level at 12,48hours of postnatal age. c. Heartrate, mean bloodpressure in the first 48 hours of life d. Hyperbilirubinemia requiring phototherapy e. Symptomatic polycythemia in first 48 hours f. Incidence of hemodynamically significant patent ductus arteriosus,NEC (Stage 2 and above), IVH on cranial ultrasound(grade3andabove), ROP(stage2andabove) and BPD g. Total number of PRBC transfusions till 6 weeks of postnatal age h. Duration of hospital stay i. Death up to 6weeks of postnatal age Timepoint: 6 weeks post-natal age	—

Measure

Time frame

a. Hct and serum ferritin at 6weeks of postnatal age b. Hb,hct and bilirubin level at 12,48hours of postnatal age. c. Heartrate, mean bloodpressure in the first 48 hours of life d. Hyperbilirubinemia requiring phototherapy e. Symptomatic polycythemia in first 48 hours f. Incidence of hemodynamically significant patent ductus arteriosus,NEC (Stage 2 and above), IVH on cranial ultrasound(grade3andabove), ROP(stage2andabove) and BPD g. Total number of PRBC transfusions till 6 weeks of postnatal age h. Duration of hospital stay i. Death up to 6weeks of postnatal age Timepoint: 6 weeks post-natal age

—

Countries

India

Contacts

Public ContactASHADUR ZAMAL

SSKM HOSPITAL

bijansaha18@gmail.com9051389120

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 5, 2026