To test efficacy of tranexamic acid in the control of bleeding in patients vomiting blood and passing blood in stools.

Efficacy of tranexamic acid and standard management vs standard management in the control of bleeding in patients with upper gastrointestinal bleed: A double-blinded randomized controlled trial - nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061840

Enrollment

252

Registered

2024-01-25

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K922- Gastrointestinal hemorrhage, unspecified

Interventions

Intervention1: TRANEXAMIC ACID: Patients allotted to the intervention group will receive TXA infusion along with standard management. TXA initial bolus of one gram (10 ml of solution) will be diluted

Eligibility

Inclusion criteria

Inclusion criteria: all patients aged above 18 years with ugi bleed

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
CONTROL OF BLEEDINGTimepoint: At baseline and then every 12th hourly for 5 days	—

Secondary

Measure	Time frame
Reducing the incidence of early re-bleeding (uptill 72 hours) Decreasing in the length of ICU and Decreasing in the in-hospital mortality rateTimepoint: 5 DAYS	—

Countries

India

Contacts

Public ContactPRABHAT KHIRWAR

JIPMER

reddy.kmc2k6@gmail.com8195014433

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026