Effect Of 5% Eutectic Mixture Of Local Anaesthetics (EMLA) Cream On Sore Throat, Cough And Hoarseness Of Voice After General Anaesthesia - A Randomized Control Trial

Effect Of 5% Eutectic Mixture Of Local Anaesthetics (EMLA) Cream Over Endotracheal Tube On Post Operative Sore Throat, Cough And Hoarseness Of Voice - A Randomized Control Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061802

Enrollment

150

Registered

2024-01-24

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: EMLA group: Application of 2 ml of 5% EMLA cream over the cuff and distal portion of endotracheal tube (outer surface) prior to intubation Control Intervention1: Nil intervention: Nil i

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 and 2 patients undergoing elective surgeries under general anaesthesia with endotracheal intubation. Expected duration of surgery is 1 to 3 hours

Exclusion criteria

Exclusion criteria: Known allergy to local anaesthetics, pre operative sore throat, difficult airway, more than 2 intubation attempts, use of throat pack, head and neck surgery involving airway, post operative mechanical ventilation, surgeries in prone position

Design outcomes

Primary

Measure	Time frame
Incidence of post operative sore throat, cough and hoarseness of voiceTimepoint: 2 hours	—

Secondary

Measure	Time frame
Incidence of post operative sore throat, cough and hoarseness of voiceTimepoint: 6 hours and 24 hours	—

Countries

India

Contacts

Public ContactDr Sandhana Inian

Sri Ramachandra Institute of Higher Education and Research

thamarai@sriramachandra.edu.in9841552333

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026