Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Control Intervention1: Neostigmine: Neostigmine will be given to one group at 0.05mg/kg I.v up to a maximum of 5 mg with glycopyrolate at 0.025mg/kg I.v
Control Intervention2: Sugammadex: Sugammadex w
Sponsors
Maulana Azad Medical College and associated Lok Nayak Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients 18 to 65 years of age 2.Patients having ASA physical status I and II 3.BMI
Exclusion criteria
Exclusion criteria: 1.Pregnant or breastfeeding women 2.Patient with history of allergy to Sugammadex, Neostigmine or Vecuronium 3.Patient with renal or hepatic impairment 4.Patient with known neuromuscular disease 5.Suspected difficult airway 6.Patients in whom satisfactory ultrasound imaging or space for placement of the ultrasonic probe will be difficult
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Mean change in TFIO from baseline to 5 minutes post extubationTimepoint: At the time of induction & 5 minutes & 30 minutes after extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Mean change in thickness fraction of internal oblique from baseline to 30 minutes post extubation. 2. Mean change in diaphragmatic thickness fraction from baseline to 5 and 30 minutes post extubation 3. Mean time to train of four ratio recovery to 0.9Timepoint: From baseline to 30 minutes and from baseline to 5 and 30 minutes post extubation. | — |
Countries
India
Contacts
Public ContactDr Priyanka
Maulana Azad Medical College and associated Lok Nayak Hospital
Outcome results
None listed