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A comparison of intranasal Midazolam and intranasal Dexmedetomidine in paediatric burn wound dressings

A comparison of intranasal Midazolam and intranasal Dexmedetomidine as premediaction for paediatric burn wound dressings: A Randomized double blind study - nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/01/061764
Enrollment
36
Registered
2024-01-23
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: nil: nil Control Intervention1: intra nasal dexmedetomidine: intra nasal dexmedetomidine Control Intervention2: intra nasal midazolam: intra nasal midazolam Control Intervention3: dexme

Sponsors

Uttar Pradesh University of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Patient of either sex belonging to ASA physical status I & II 2)Patients undergoing burn wound dressing. 3)Area of burn 4)Ist and IInd degree burn

Exclusion criteria

Exclusion criteria: 1)Patient refusal 2)Anticipated difficult airway 3)IIIrd degree burn 4)Patient having prior history of allergy with any of the drugs used in the study. 5)Patients with recent upper respiratory tract infection/ lower respiratory tract infection, nasal obstruction (mass), epistaxis, nasal congestion, sinusitis, congenital heart disease, mental retardation, or neurobehavioral problems. •Patients with extensive burns involving the upper extremities, with no place for the attachment of blood pressure apparatus or pulse oximeter probes, were also excluded.

Design outcomes

Primary

MeasureTime frame
Ramsay Sedation ScaleTimepoint: 5, 10, 15, 20, 25, and 30 min after drug administration

Secondary

MeasureTime frame
hemodynamic parametersTimepoint: baseline,5, 10, 15, 30 min after drug administration.

Countries

India

Contacts

Public ContactShuchi Nigam

Uttar Pradesh University of Medical Sciences, Saifai

shuchinigam@gmail.com7017954040

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026