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COMPARE RESULTS OF GASTRIC ASPIRATE SMEAR CBANAAT WITH BRONCHOALVEOLAR LAVAGE SMEAR AND CBNAAT

COMPARATIVE STUDY OF GASTRIC ASPIRATE AND BRONCHOALVEOLAR LAVAGE SMEAR AND CBNAAT EXAMINATION FOR DIAGNOSIS OF PULMONARY TUBERCULOSIS IN SPUTUM SMEAR NEGATIVE SUSPECTED PATIENTS

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/01/061762
Enrollment
100
Registered
2024-01-23
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A150- Tuberculosis of lung

Interventions

Intervention1: GASTRIC ASPIRATE: For Gastric Aspirate- GA specimens will be obtained early in the morning, before breakfast. This technique involves inserting a nasogastric tube into the patient, rins
local anaesthesia( 2% lignocaine) and sedation( fentanyl and midazolam) will be administered. After the bronchial tree inspection, 60–100 mL of normal saline will be instilled and aspirated from lung

Sponsors

ABHI MUKHARYA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age more than 18 years having two sputum smear negative Patient with high clinical and radiological suspicion of Pulmonary Tuberculosis [Suspicion will be made on the basis of- Persistent cough (more than 2 weeks), Fever, Persistent radiological infiltrates (CXR showing atelectasis, consolidation, cavitation or effusion, infiltration) not responding to antimicrobials]

Exclusion criteria

Exclusion criteria: Patient having history of taking anti-tubercular medication Patients with contraindications of bronchoscopy like Patients with hypoxia (SpO2 Patients having history malignant hyperthermia Patients with contraindiacation to anesthesia. Patients with bleeding diathesis Hemodynamically unstable patients. 3. Pregnant female patients

Design outcomes

Primary

MeasureTime frame
To compare smear result of gastric aspirate with bronchoalveolar lavage in sputum smear negative patientsTimepoint: 1 year

Secondary

MeasureTime frame
To compare CBNAAT result of gastric aspirate with bronchoalveolar lavage in sputum smear negative patients Timepoint: 1 year

Countries

India

Contacts

Public ContactJIGNA DAVE

SIR T HOSPITAL BHAVNAGAR

drjignadave@yahoo.co.in9825096289

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026