The effect of different sounds and external electrical pulses on ringing of ears.

A study to evaluate the efficacy of vagus nerve stimulation and acoustic stimuli coupling in reducing tinnitus-related distress for chronic subjective tinnitus: a randomised controlled trial (RCT). - AVNST

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061746

Enrollment

Registered

2024-01-23

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H931- Tinnitus

Interventions

Intervention1: VNS + matched noise: Non-invasive transcutaneous auricular vagus nerve stimulation provided using Neurostim device (NS2, Medicaid Systems, Punjab, India) at Cymba Concha of left ear at

Eligibility

Inclusion criteria

Inclusion criteria: Medically stable male and female adults with chronic, subjective, tonal, continuous Unilateral or bilateral tinnitus Chronic tinnitus defined as tinnitus onset for more than 3 months

Exclusion criteria

Exclusion criteria: Acute, intermittent, noise-like, objective tinnitus Undergoing any tinnitus treatment in last month Associated otological, neuropsychiatric, respiratory, cardiac, dermatological problems Pregnant or breastfeeding Functioning embedded device Consuming medications recognised to modulate neuromodulators Hearing loss greater than 60dBHL

Design outcomes

Primary

Measure	Time frame
Tinnitus Loudness, Tinnitus Functional IndexTimepoint: Post-treatment	—

Secondary

Measure	Time frame
Tinnitus Loudness, Tinnitus Functional IndexTimepoint: 1-month post-treatment follow-up	—

Countries

India

Contacts

Public ContactDr Sanjay Munjal

Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh

himanshu.dudeja14@gmail.com9711768938

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026