Health Condition 1: J984- Other disorders of lung
Conditions
Interventions
Intervention1: BOVINE LIPID EXTRACT SURFACTANT: Bovine Lipid Extract Surfactant(Neosurf®) at a dose of 135mg/kg( 5ml/kg)
Control Intervention1: PORCINE DERIVED SURFACTANT: Poractant-a (Curosurf®) at a
Sponsors
IPGMER AND SSKM HOSPITAL
Eligibility
Inclusion criteria
Inclusion criteria: •Intramural Preterm babies with gestational age between 28 to 34 weeks diagnosed with RDS and eligible for surfactant administration by LISA technique will be enrolled in this study
Exclusion criteria
Exclusion criteria: • Baby with major congenital anomaly • Perinatal asphyxia • Intubated at the delivery room • An alternative cause of respiratory distress • Any baby requiring mechanical ventilation and surfactant administration
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Requirement for intubationTimepoint: WITHIN 72 HOURS OF LIFE | — |
Secondary
| Measure | Time frame |
|---|---|
| •Complications occurring during the procedure •Need for the second dose of Surfactant •Duration of respiratory support •Pulmonary haemorrhage •Pulmonary air leak syndromes •Hemodynamically significant PDA requiring treatment •Grade 3 & grade 4 IVH •Periventricular Leukomalacia •ROP requiring Laser treatment •NEC stage 2 & above •Duration of hospital stay •Bronchopulmonary dysplasia(BPD) •Death before hospital discharge Timepoint: TILL THE HOSPITAL DISCHARGE | — |
Countries
India
Contacts
Public ContactDR ASHADUR ZAMAL
IPGMER AND SSKM HOSPITAL
Outcome results
None listed