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Comparison of Vitamin C injection and Diode laser for gum depigmentation.

Comparative evaluation of vitamin c mesotherapy and soft tissue diode laser for gingival depigmentation: A Split mouth clinical trial.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/01/061700
Enrollment
10
Registered
2024-01-22
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K055- Other periodontal diseases

Interventions

Intervention1: Vitamin C mesotherapy: Participants will be subjected to oral prophylaxsis prior to the procedure. Topical anaesthetic gel will be applied over the area of interest. Vitamin C (l ascor

Sponsors

Nivethitha R
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Systemically healthy participants . 2) Presence of physiologic gingival pigmentation (Score =1 on Melanin pigmentation index by Kumar et al.). 3) Participants with a gingival index score = 1.( Loe and silness).

Exclusion criteria

Exclusion criteria: 1) Pregnant and lactating mothers. 2) Usage of chlorohexidine or povidone iodine mouthwash. 3) Participants under medication that can cause gingival pigmentation. 4) Participants who use any form of tobacco. 5) Known hypersensitivity to ascorbic acid . 6) Participants who had undergone depigmentation procedures previously. 7) Pigmentation due to exogenous source (eg. lead, mercury, silver, arsenic etc.,)

Design outcomes

Primary

MeasureTime frame
To evaluate and compare effectiveness of Vitamin C and diode laser for depigmentation.Timepoint: At baseline, 1 month, 3 months and 6 months

Secondary

MeasureTime frame
To compare wound healing after Vitamin C and diode laser depigmentation.Timepoint: 1 week post-op;To evaluate Repigmentation after Vitamin C and diode laser depigmentation.Timepoint: 1 month, 3 months and 6 months post op.

Countries

India

Contacts

Public ContactNivethitha R

Yenepoya Dental College

shruthyprathap@gmail.com9980433489

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026