Comparison of Ropivacaine vs Ropivacaine with Dexmedetomidine for Axillary Plexus Block in patients undergoing forearm and hand surgery.

A Double Blind Randomized Controlled Study For Evaluating The Role Of Dexmedetomidine as Adjuvant To 0.5% Ropivacaine In Axillary Plexus Block for Patients Undergoing Forearm And Hand Surgery. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061691

Enrollment

100

Registered

2024-01-22

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Axillary Plexus Block with 0.5% Ropivacaine and Dexmedetomidine (100 mcg): 30 ml of 0.5% Ropivacaine (150 mg) and 2 ml Dexmedetomidine (100 mcg)

Dose: Ropivacaine (2 - 3 mg/kg), Dexmedetomedine (1 - 1.2 mcg/kg)

Frequency: Ones

Site: Perineural infiltration of brachial plexus by axillary approach. Duration of procedure: 10 minutes Control Intervention1: Axillary Plexus Block with 0.5% Ropivacaine and Distilled water (2 ml):

Dose: Ropivacaine (2 - 3 mg/kg)

Site: Perineural infiltration of brachial plexus by axillary approach. Duration of procedure: 10 minutes

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA Grade I and II. 2. Enrolled for elective forearm and hand surgery.

Exclusion criteria

Exclusion criteria: 1. Any known hypersensitivity or contraindication to ropivacaine, dexmedetomidine 2. Pregnancy, lactating mothers 3. Hepatic, renal or cardiopulmonary abnormality, 4. Alcoholism, diabetes, long-term analgesic therapy 5. Bleeding diathesis, local skin site infections 6. History of significant neurological, psychiatric or neuromuscular disorders 7. Patients having any history of drug allergy or prolonged drug treatment.

Design outcomes

Primary

Measure	Time frame
To compare the mean duration of analgesia between two groups.Timepoint: Post operative period	—

Secondary

Measure	Time frame
1. To compare the onset of sensory and motor block among the two groups. 2. To compare the haemodynamic changes among two groups. 3. To compare the time for administration of first rescue analgesics among two groups.Timepoint: Peri operative period	—

Countries

India

Contacts

Public ContactProf Dr Anjan Das

College of Medicine and Sagore Dutta Hospital

anjan2k8@yahoo.com9874171440

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026