Comparison of haemodynamic response with three different techniques of endotracheal intubation in patients undergoing craniotomy under general anaesthesia

Comparison of three different techniques of endotracheal intubation in patients undergoing craniotomy under general anaesthesia- Macintosh direct laryngoscopy versus KingvisionÂ® channelled video laryngoscopy versus BlockbusterÂ® LMA guided blind intubation. A prospective randomised controlled study - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061674

Enrollment

150

Registered

2024-01-19

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Macintosh blade direct laryngoscope: Endotracheal intubation using Macintosh blade direct laryngoscope Intervention2: Curved blade channelled video laryngoscope: Endotracheal intubation

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients belonging to ASA grades- I, II and III 2. Patients undergoing elective craniotomies for non- vascular intracranial lesions

Exclusion criteria

Exclusion criteria: 1. Patients having anticipated difficult airways 2. Patients having hypertension or diabetes mellitus 3. Patients on any drug known to affect heart rate and blood pressure 4. Patient refusal to participate

Design outcomes

Primary

Measure	Time frame
To compare heart rate and blood pressure changes triggered by the three different techniques of endotracheal intubation- direct laryngoscopy, KingvisionÂ® chanelled video laryngoscopy, BlockbusterÂ® LMA guided technique.Timepoint: primary outcome variables will be measured at the following time points: 1. Baseline 2. Following neuromuscular blockade 3. Immediately after endotracheal intubation 4. 4 more readings at 1 minute intervals starting from the previous recording	—

Measure

Time frame

To compare heart rate and blood pressure changes triggered by the three different techniques of endotracheal intubation- direct laryngoscopy, KingvisionÂ® chanelled video laryngoscopy, BlockbusterÂ® LMA guided technique.Timepoint: primary outcome variables will be measured at the following time points: 1. Baseline 2. Following neuromuscular blockade 3. Immediately after endotracheal intubation 4. 4 more readings at 1 minute intervals starting from the previous recording

—

Secondary

Measure	Time frame
1. To compare the number of intubation attempts between the three groups 2. To compare the additional manipulations required for intubation in the three groups 3. To study the glottic view (Cormackâ??Lehane) 4. To record traumatic complications caused by intubation procedure Timepoint: 1st, 2nd & 3rd outcome to be measured at single time point during endotracheal intubation. 4th outcome will be measured immediately postoperatively in the recovery room or ICU	—

Measure

Time frame

1. To compare the number of intubation attempts between the three groups 2. To compare the additional manipulations required for intubation in the three groups 3. To study the glottic view (Cormackâ??Lehane) 4. To record traumatic complications caused by intubation procedure Timepoint: 1st, 2nd & 3rd outcome to be measured at single time point during endotracheal intubation. 4th outcome will be measured immediately postoperatively in the recovery room or ICU

—

Countries

India

Contacts

Public ContactSreyashi Naskar

Bangur Institute of Neurology, IPGME&R and SSKM Hospital

dr.amitaacharya@yahoo.com8017624698

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026