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Effectiveness of Magnetic Stimulation of Brain in Treatment of Generalized Anxiety Disorder

To Assess and Compare Short term Efficacy of Adjunctive continuous theta burst stimulation over posterior parietal cortex in Generalized anxiety disorder: A randomized sham controlled study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/01/061662
Enrollment
44
Registered
2024-01-19
Start date
Unknown
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F411- Generalized anxiety disorder

Interventions

Intervention1: Unilateral continuous theta burst magnetic stimulation: cTBS (Posterior Parietal cortex) will be delivered in two sessions (half an hour apart) per day for 5 days in a week Control Inte

Sponsors

Sri Guru Ram Rai Institute of Medical and Health Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient with a diagnosis of Generalized anxiety disorder based on diagnostic criteria of Diagnostic and Statistical Manual of mental disorder, fifth edition (DSM-5), or International Classification of Disease (ICD-11). 2.Patients aged between 18-59 years 3.Patients giving written consent to participate in protocol. 4.Right-handed, normotensive patient. 5.Severity of illness: HAM-A score >18 or Clinical Global Impression–Severity score of 4 or greater.

Exclusion criteria

Exclusion criteria: 1.Patient is uncooperative for the procedure. 2.Patients with neurological disorders with history of epilepsy, organic brain damage or any neurological procedures. 3.Patients with mild to moderate depression (HAM-D score >13). 4.Patients with implanted metallic devices. 5. Patients receiving ECT in past 6 months. 6. Patients with other neurovascular comorbidities (tumor, cerebro-vascular events, cranio-encephalic trauma). 7. Significant unstable medical condition like uncontrolled hypertension, complicated diabetes mellitus or any organ failure. 8. Patients with psychotic disorders and substance use disorders, except nicotine and caffeine (as per DSM-5)

Design outcomes

Primary

MeasureTime frame
To assess and compare in the anxiety symptoms in patients suffering from Generalized Anxiety Disorder following continous theta burst stimulation in "active" and "sham" group.Timepoint: The patient will be assessed using HAM-A, CGI-S and WHOqol-BREF at baseline, 7th day and 21st day—

Secondary

MeasureTime frame
To assess illness severityTimepoint: CGI applied at Day0,7 and 21 days;To assess quality of lifeTimepoint: WHO-QOL applied at Day 0, 7 and 21 days—

Countries

India

Contacts

Public ContactSarthak Bhandari

Sri Guru Ram Rai Institute of Medical and Health Sciences

dhyani.mohan@gmail.com9997688192

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026