Comparison of safety of transdermal ketoprofen and diclofenac patches in post-operative pain management

Comparison of efficacy and safety of single dose transdermal ketoprofen and diclofenac patches in post-operative pain management in patients undergoing lower limb orthopedic procedures - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061659

Enrollment

Registered

2024-01-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical

Interventions

Control Intervention1: diclofenac 100 mg transdermal patch.: 35 patients assigned in Group D received transdermal diclofenac 100 mg. In the immediate postoperative period no other analgesics were give

Eligibility

Inclusion criteria

Inclusion criteria: who were all undergoing lower limb surgeries (ORIF).

Exclusion criteria

Exclusion criteria: pregnant or lactating mothers, patients on chronic pain treatment, patients with known allergy to the study drug, with any bleeding disorders, with history of impaired cognitive functions and history of alcohol and substance abuse.

Design outcomes

Primary

Measure	Time frame
postoperative pain was taken in a visual analogue scaleTimepoint: visual analogue scale (VAS) were used. VAS score was recorded at 4,6,8,12 and 24 hours postoperatively	—

Secondary

Measure	Time frame
Sleep interference score was also recorded on a 10-point scaleTimepoint: how the pain had interfered with patient’s sleep during the first 24 hours	—

Countries

India

Contacts

Public ContactPavithira Sekar

Sri Lalithambigai medical college

drpavithras06@gmail.com9940087476

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026