This study is being done to compare the analgesic and hemodynamic effect of administration of Fentanyl, an opioid analgesic mixed with Bupivacaine, a Local Anaesthetic for Spinal Anaesthesia using two different methods in patients undergoing Lower Abdominal Surgeries.

Comparison of efficacy of hyperbaric bupivacaine pre-mixed with fentanyl versus sequential administration of fentanyl followed by hyperbaric bupivacaine in lower abdominal surgery - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061656

Enrollment

Registered

2024-01-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Sequential Injection of Fentanyl with Hyperbaric Bupivacaine: 25 mcg of Fentanyl will be loaded in a 2 ml syringe and 15 mg of Hyperbaric Bupivacaine(0.5%) will be loaded in a 5 ml syri

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing lower abdominal surgery American Society of Anaesthesiologits Grade 1 and 2

Exclusion criteria

Exclusion criteria: Patients with history of opioid intake Patients who refuse to participate in the study Patients with known allergy to drugs used in the study

Design outcomes

Primary

Measure	Time frame
Compare the onset and completion of sensory and motor blockade in both groupsTimepoint: The sensory and motor blockade will be assessed continuously till the achievment of onset and completion of blockade (5-20 mins).	—

Secondary

Measure	Time frame
Compare the hemodynamic effect, duration of block, requirement of rescue analgesia and adverse events in both groupsTimepoint: Immedicately after the block and at every 1 minute interval for the first 5 minutes and then till 10 minutes	—

Countries

India

Contacts

Public ContactDr Sagnik Datta Majumdar

Chirayu Medical College and Hospital

drst23@gmail.com7042461338

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026