Comparing the effectiveness of two local anaesthetic drugs as an additive in epidural labour analgesia

A comparative study on the efficacy of Dexmedatomidine and Fentanyl as a local anaesthetic adjuvant to Levobupivacaine 0.125% in epidural labour analgesia- A randomized controlled study - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061650

Enrollment

Registered

2024-01-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80- Encounter for full-term uncomplicated delivery

Interventions

Intervention1: Levobupivacaine: Levobupivacaine 0.125% in epidural labor analgesia, for 3- 6 hours Control Intervention1: Addititive:Dexmedetomidine Addititive:Fentanyl: Dexmedetomidine- 0.5mcg/Kg Fe

Eligibility

Inclusion criteria

Inclusion criteria: Age > 18 years Full term primigravida with singleton pregnancy ( >37 weeks gestation) and required labor analgesia in hospital Patients who met the criteria for American Society of Anaesthesiology physical status I/II Patients willing to participate in the trial

Exclusion criteria

Exclusion criteria: 1)Severe Heart, Lung, Liver and Kidney diseases,hemorraghic diseases or other systemic diseases 2)Known genteic or congenital malformations, fetal growth restrictions or Oligohydramnios. 3)Lower abdominal or urological surgery history, spinal deformity or previous spinal surgery

Design outcomes

Primary

Measure	Time frame
TO COMPARE THE ANALGESIC EFFECTS IN BOTH THE GROUPS FOR THE MOTHERTimepoint: Intraoperative period	—

Secondary

Measure	Time frame
COMPARING THE EFFECTIVENESS OF DEXMEDETOMIDINE AND FENTANYL AS A LOCAL ANESTHETIC ADJUVANT TO LEVOBUPIVACAINE IN EPIDURAL LABOR ANELGESIATimepoint: Intraoperative period.	—

Countries

India

Contacts

Public ContactKRISHNA PRASAD T

Shri Sathya Sai Medical College and Research Institute

drkrishna86@gmail.com9944579455

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026