Health Condition 1: G969- Disorder of central nervous system, unspecified
Conditions
Interventions
Intervention1: Intranasal midazolam spray: 0.5mg/puff (to be given as 0.2 mg/kg/dose), given once.
Control Intervention1: Intravenous midazolam: 0.1-0.2mg/kg/dose, Given once
Sponsors
Government medical college and hospital, Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: All children between the ages of 1 month and 18 years presenting with acute seizures for at least 5 minutes duration in pediatric emergency and in patient department of GMCH 32, Chandigarh
Exclusion criteria
Exclusion criteria: 1) Non consenting parents 2) Children 3) Children with upper respiratory tract infections 4) Children who had received anticonvulsants within 1 hour before admission 5) Children with severe cardiorespiratory decompensation 6) Children with CSF rhinorrhea 7) Known allergy to benzodiazepines.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Seizure cessationTimepoint: Interval between arrival of patients at the hospital with active seizures/ witnessed seizures more than 5 minutes and the control of seizures | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse drug reactions among the patients receiving intranasal & intravenous midazolam.Timepoint: 30 minutes | — |
Countries
India
Contacts
Public ContactDr Sherlin Jeberzhiah
Government medical college and hospital, Chandigarh,
Outcome results
None listed