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Histopathology of Female Urethral Strictures

Histologic Analysis of Female Urethral Strictures Following Dorsal On lay Buccal Mucosal Graft Urethroplasty - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/01/061636
Enrollment
30
Registered
2024-01-19
Start date
Unknown
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N359- Urethral stricture, unspecified

Interventions

Intervention1: NIL: NIL

Sponsors

Department of Urology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Females aged 18 years or above with urethral stricture disease confirmed by uroflowmetry and cystoscopy. 2. Females who undergo a dorsal onlay buccal mucosal graft urethroplasty. 3. Written informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients who have undergone surgery for urethral stricture disease previously 2. Patients in whom ventral BMGU is performed. 3. Patients with STDs 4. Patients with genitourinary anomalies 5. Patients who have had surgery for hypertrophy of the bladder neck 6. Patients who have had radiation to the pelvis 7. Patients with bladder malignancies

Design outcomes

Primary

MeasureTime frame
a)Evaluation for epithelial hyperplasia and cell typeTimepoint: 10 days

Secondary

MeasureTime frame
a) To evaluate the presence of mucosal oedema b) To evaluate the degree of fibroblast/inflammatory cell infiltrate c) To evaluate the elastin fibre distribution. Timepoint: baseline, 4 weeks

Countries

India

Contacts

Public ContactPrasanna Ram

All India Institute of Medical Sciences

dr.praspr@gmail.com9686559576

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026