A scientific experiment to evaluate and compare the efficacy of intravenous Lidocaine and Dexamethasone in terms of attenuation of Propofol injection pain during induction of Anaesthesia

A Prospective Randomized Comparative study of the effect of intravenous Lidocaine versus Dexamethasone on Propofol injection pain - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061575

Enrollment

Registered

2024-01-18

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: GROUP A: Intravenous Lidocaine preservative free 40mg in 2ml of 2 % as pretreatment in 50seconds Control Intervention1: Group B: Intravenous Dexamethasone 8mg in 50 seconds

Eligibility

Inclusion criteria

Inclusion criteria: ALL ASA Grade I AND II patients undergoing elective Surgeries under General Anaesthesia

Exclusion criteria

Exclusion criteria: All ASA grade III and IV patients Cardiovascular, respiratory and neurological disorders Patients allergic to Propofol and study drugs(soya bean oil,MCT,glycerol,egg lecithin and sodium oleate) Patients in whom hand or forearm veins not accessible Patients having problems in communication

Design outcomes

Primary

Measure	Time frame
Verbal Numerical Rating scaleTimepoint: assessed 50 seconds after intravenous injection of Propofol	—

Secondary

Measure	Time frame
Mc Crirrick & Hunter pain intensity scaleTimepoint: After 50 seconds of intravenous injection of Propofol before patient loses consciousness	—

Countries

India

Contacts

Public ContactDr Aparna P

Mysore Medical College and Research Institute

dineshgovindarao@gmail.com9845582006

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026