Comparison of the effect of prophylactic bolus of ephedrine versus norepinephrine to prevent post-spinal hypotension during elelctive caesarean section under spinal anaesthesia.

Comparison of the effect of prophylactic bolus of ephedrine versus norepinephrine to prevent post-spinal hypotension during elelctive caesarean section under spinal anaesthesia-a randomised controlled double blind study. - NIL

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061565

Enrollment

100

Registered

2024-01-18

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 1- Obstetrics

Interventions

Intervention1: During spinal anaesthesia, a prefilled 1ml syringe of prophylactic bolus dose of 6 mg (1 ml) Ephedrine will be given.: Patients undergoing elective ceserean section under spinal anaest

Eligibility

Inclusion criteria

Inclusion criteria: Willing to participate ASA class 2

Exclusion criteria

Exclusion criteria: Pregnant women with pre-eclampsia and eclampsia Baseline bp >140mmhg BMI >30kg/m2 Comorbid conditions (cardiovascular, renal,hepatic diseases) Contraindication to spinal anaesthesia like coagulopathy,raised ICP Failed spinal anaesthesia

Design outcomes

Primary

Measure	Time frame
Decreased incidence of post spinal hypotension with norepinephrine than ephedrine.Timepoint: 2 years	—

Secondary

Measure	Time frame
Effective prevention of adverse effects like nausea, vomiting secondary to hypotension & improved neonatal outcome with norepinephrine than ephedrine.Timepoint: 2 years	—

Countries

India

Contacts

Public ContactAkshata K Hiremath

SDM college of Medical Sciences and Hospital

kadurgolightly@gmail.com9782560622

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026