To find out the effect of human growth factors in the treatment of mild to moderate gum recession

A comparative clinical evaluation of human chorion membrane(CM) with and without autologous platelet rich fibrin(PRF) in the treatment of gingival recession defects in stage I and II periodontitis patients: A randomized clinical trial. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/01/061514

Enrollment

Registered

2024-01-16

Start date

Unknown

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Surgical Therapy: Coronally advanced flap surgery and placement of human chorion membrane with and without autologous advanced platelet rich fibrin plus Control Intervention1: Advanced

Eligibility

Inclusion criteria

Inclusion criteria: a. Patients within age group of 18 – 60 years. b. Participants maintaining good oral hygiene after completion of scaling and root planing. c. Patient with at least two non-adjacent maxillary and mandibular anterior and premolar teeth with Millers Grade I and II gingival recession defects.

Exclusion criteria

Exclusion criteria: a. Patients with chronic diseases such as Diabetes mellitus, arthritis, thyroid disorder, etc. b. Patients using protective or orthodontic appliances c. Patients who are smokers or using any other tobacco products d. Female patients who are pregnant and lactating.

Design outcomes

Primary

Measure	Time frame
Root coverage Timepoint: Root coverage will be assessed at baseline (on the day of surgery), 1week, 4 weeks & 12 weeks.	—

Secondary

Measure	Time frame
1. Clinical attachment level 2. Gingival tissue thickness 3. Gingival IndexTimepoint: clinical parameters will be assessed at baseline (on the day of surgery), 1week, 4 weeks & 12 weeks.	—

Countries

India

Contacts

Public ContactDr Kunal S Sethi

MGVS KBH Dental College and Hospital

kunalks2001@yahoo.com9823020048

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026